Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.50 |
| ▸ | CHRNG | P07510 | 1/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215425 | 0.77 | PTPN1 (0.39) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10932919 | 0.77 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10216781 | 0.75 | HTT (0.33) | RARGRARB | |
| SCHEMBL10214253 | 0.75 | KLKB1 (0.37) | RARGRARB | |
| SCHEMBL5768474 | 0.73 | CHRNB2 (0.82) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| Hydrochloric Acid SCHEMBL6395673 | 0.72 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL4404495 | 0.67 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10170777 | 0.67 | CHRNA1 (0.53) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL11115696 | 0.67 | CHRNA1 (0.53) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 | |
| SCHEMBL18527158 | 0.66 | CHRNA1 (0.49) | CHRNB2CHRNA4CHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040962-A1 | FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040962-A1 | FUSED RING INHIBITORS OF HEPATITIS C | HAVCR2, HCCS, ZC3HAV1 | CHRNB2 4779/4885CHRNA4 4862/4885CHRNA1 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.