⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL29112829 | 0.87 | NOS2 (0.75) | — | |
| SCHEMBL17551 | 0.78 | — | — | |
| SCHEMBL1653770 | 0.78 | — | — | |
| SCHEMBL31105996 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL27833646 | 0.76 | NOS2 (0.61) | — | |
| SCHEMBL2828386 | 0.76 | — | — | |
| SCHEMBL1019361 | 0.74 | — | — | |
| SCHEMBL91461 | 0.74 | — | — | |
| SCHEMBL18712146 | 0.74 | — | — | |
| SCHEMBL558598 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| US-9701691-B2 | Thienopyrimidine compounds | HOFFMAN-LA ROCHE INC. (US) | 2017-07-11 | — | — | US | claimed |
| EP-2802590-B1 | THIENOPYRIMIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-03-01 | — | — | EP | claimed |
| EP-2802590-A1 | THIENOPYRIMIDINE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2014-11-19 | — | — | EP | claimed |
| CN-101657480-B | Alkali-developable resins, method for preparing the same and photosensitive composition comprising the alkali-developable resins | LG CHEMICAL LTD | 2013-09-04 | — | — | CN | claimed |
| WO-2013104575-A1 | THIENOPYRIMIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-07-18 | — | — | WO | claimed |
| US-20130178460-A1 | THIENOPYRIMIDINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2013-07-11 | — | — | US | claimed |
| CN-102126951-A | Crosslinkable compound and photosensitive composition comprising the same | LG CHEMICAL LTD | 2011-07-20 | — | — | CN | claimed |
| CN-101657480-A | Alkali-developable resins, its preparation method and comprise the photosensitive composition of this alkali-developable resins | LG CHEMICAL LTD KR | 2010-02-24 | — | — | CN | claimed |
| US-12441724-B2 | Inhibitors of plasma kallikrein and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-10-14 | — | — | US | disclosed |
| EP-4615839-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | Bristol-Myers Squibb Company (US) | 2025-09-17 | — | — | EP | disclosed |
| CN-120152973-A | Protein tyrosine phosphatase inhibitors, compositions, and methods of use | 百时美施贵宝公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| CN-1194996-A | Photocrosslinkable polymers | ROLIC AG (CH) | 1998-10-07 | — | — | CN | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |
| WO-1992007468-A1 | HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-14 | — | — | WO | disclosed |
| WO-1991017979-A1 | PROCESS FOR THE PREPARATION OF 2-N-ACYLAMINOPYRIDINES AND 2-AMINOPYRIDINES FROM 5-OXOALKANENITRILE OXIMES | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |
| EP-0135833-B1 | METHOD FOR THE PREPARATION OF 2-AMINO-ALKYLPYRIDINES | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| US-4628097-A | Process for the preparation of 2-amino-alkylpyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |