Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10216710 | 0.90 | ADORA1 (0.53) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL396360 | 0.88 | ADORA1 (0.69) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL10216687 | 0.86 | GRM5 (0.46) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL10216659 | 0.86 | GRM5 (0.45) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL10216663 | 0.82 | GRM5 (0.43) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL10216643 | 0.80 | GRM5 (0.43) | ADORA1ADORA2AADORA2BGRM5KDM4E | |
| SCHEMBL398975 | 0.80 | ADORA1 (0.62) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL395677 | 0.79 | ADORA1 (0.66) | ADORA1ADORA2AADORA2BGRM5CYP1A2 | |
| SCHEMBL10216702 | 0.79 | GRM5 (0.42) | ADORA1ADORA2AADORA2BGRM5KDM4E | |
| SCHEMBL10216672 | 0.78 | ADORA1 (0.59) | ADORA1ADORA2AADORA2BCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101290-B2 | Organic compound having electron-transporting and/or hole-blocking performance and its use and OLEDs comprising the compound | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) | 2012-01-24 | — | — | US | disclosed |
| US-20090102356-A1 | NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090102356-A1 | NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND | SLCO4C1, SLCO1B1, SLCO2B1 | ADORA1 3214/4885ADORA2A 2414/4885ADORA2B 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.