Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.61 |
| ▸ | GRM5 | P41594 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439172 | 0.93 | ADORA1 (0.56) | ADORA1ADORA2AGRM5HSD17B10ADORA2B | |
| SCHEMBL396360 | 0.91 | ADORA1 (0.69) | ADORA1ADORA2AGRM5ADORA2BALDH1A1 | |
| SCHEMBL395158 | 0.91 | GRM5 (0.56) | ADORA1ADORA2AGRM5HSD17B10ADORA2B | |
| SCHEMBL24577294 | 0.88 | ADORA1 (0.51) | ADORA1ADORA2AGRM5HSD17B10ADORA2B | |
| SCHEMBL10270250 | 0.87 | GRM5 (0.55) | ADORA1ADORA2AGRM5ADORA2BALDH1A1 | |
| SCHEMBL10270112 | 0.87 | GRM5 (0.55) | ADORA1ADORA2AGRM5ADORA2BALDH1A1 | |
| SCHEMBL399546 | 0.82 | GRM5 (0.51) | ADORA1ADORA2AGRM5ADORA2BALDH1A1 | |
| SCHEMBL396579 | 0.82 | GRM5 (0.51) | ADORA1ADORA2AGRM5ADORA2B | |
| SCHEMBL395677 | 0.81 | ADORA1 (0.66) | ADORA1ADORA2AGRM5ADORA2BALDH1A1 | |
| SCHEMBL12681373 | 0.80 | ALDH1A1 (0.55) | ADORA1ADORA2AHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101290-B2 | Organic compound having electron-transporting and/or hole-blocking performance and its use and OLEDs comprising the compound | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) | 2012-01-24 | — | — | US | disclosed |
| US-8101290-B2 | Organic compound having electron-transporting and/or hole-blocking performance and its use and OLEDs comprising the compound | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) | 2012-01-24 | — | — | US | disclosed |
| US-20090102356-A1 | NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) | 2009-04-23 | — | — | US | disclosed |
| US-20090102356-A1 | NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090102356-A1 | NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND | SLCO4C1, SLCO1B1, SLCO2B1 | ADORA1 3214/4885ADORA2A 2414/4885GRM5 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.