Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636110 | 0.79 | EPHX2 (0.55) | L3MBTL1EPHX2EPHX1MEN1MAPK1 | |
| SCHEMBL636111 | 0.79 | EPHX2 (0.55) | L3MBTL1EPHX2EPHX1MEN1MAPK1 | |
| SCHEMBL18720743 | 0.75 | EPHX1 (0.39) | L3MBTL1EPHX2TRPV1EPHX1KMT2A | |
| SCHEMBL18720725 | 0.74 | KMT2A (0.39) | L3MBTL1EPHX2TRPV1EPHX1KMT2A | |
| SCHEMBL23900514 | 0.71 | EPHX2 (0.37) | EPHX2EPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL18720724 | 0.71 | EPHX2 (0.40) | EPHX2EPHX1KMT2AALDH1A1LMNA | |
| SCHEMBL18671588 | 0.70 | GAA (0.34) | L3MBTL1EPHX2TRPV1EPHX1MEN1 | |
| SCHEMBL19841736 | 0.70 | GAA (0.34) | L3MBTL1EPHX2TRPV1EPHX1MEN1 | |
| SCHEMBL16365922 | 0.69 | EPHX2 (0.48) | EPHX2EPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL13711391 | 0.68 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086995-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-02-22 | — | — | EP | disclosed |