Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.82 |
| ▸ | ROCK1 | Q13464 | 13/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | BLK | P51451 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | STK3 | Q13188 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040576 | 0.90 | ROCK2 (1.00) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL17040581 | 0.88 | ROCK2 (0.87) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL30743051 | 0.82 | ROCK2 (1.00) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL877829 | 0.82 | ROCK2 (1.00) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL17041187 | 0.82 | ROCK2 (0.75) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL17041039 | 0.82 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL17040608 | 0.79 | ROCK2 (0.67) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL882770 | 0.79 | ROCK2 (0.81) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL24271460 | 0.79 | ROCK2 (0.62) | ROCK2ROCK1CLK2BLKCSNK2A1 | |
| SCHEMBL17038102 | 0.78 | ROCK2 (1.00) | ROCK2ROCK1CLK2BLKCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040499-A2 | METABOLIC INHIBITORS | SURFACE LOGIX, INC. (US) | 2012-03-29 | — | — | WO | disclosed |