Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18705054 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTHRH3CYP2D6EPHX2 | |
| SCHEMBL2948497 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTHRH3CYP2D6ACKR3 | |
| SCHEMBL12026487 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTHRH3CYP2D6EPHX2 | |
| SCHEMBL24629364 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTHRH3CYP2D6EPHX1 | |
| SCHEMBL12885053 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTHRH3CYP2D6EPHX2 | |
| SCHEMBL24474299 | 0.80 | EPHX1 (0.66) | ALDH1A1MAPTHRH3CYP2D6EPHX2 | |
| SCHEMBL2609287 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTHRH3CYP2D6EPHX2 | |
| SCHEMBL2106067 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTHRH3CYP2D6EPHX2 | |
| SCHEMBL10271099 | 0.79 | EPHX2 (0.46) | ALDH1A1EPHX2EPHX1CYP3A4 | |
| SCHEMBL18705061 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTHRH3CYP2D6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | ALDH1A1 1821/4885MAPT 4787/4885HRH3 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.