Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | HTR1D | P28221 | 3/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271922 | 0.86 | CYP1A2 (0.59) | HTR2CHTR1DHRH4HTR3EHTR3B | |
| SCHEMBL31652347 | 0.78 | CYP1A2 (0.72) | HTR2CHRH4ADRB2NCF1ADRB1 | |
| SCHEMBL7243793 | 0.78 | HRH4 (0.51) | HRH4NCF1HRH3ADRB1HTR3E | |
| SCHEMBL4472647 | 0.78 | CYP1A2 (0.72) | HTR2CHRH4ADRB2NCF1ADRB1 | |
| SCHEMBL24969921 | 0.76 | HTR1D (0.54) | HTR2CHTR1DHRH4ADRB2NCF1 | |
| SCHEMBL31142915 | 0.76 | HTR1D (0.54) | HTR2CHTR1DHRH4ADRB2NCF1 | |
| SCHEMBL7243017 | 0.76 | HRH4 (0.69) | HRH4ADRB1CYP1A2 | |
| SCHEMBL10219267 | 0.76 | ENPP2 (0.47) | ALDH1A1MAPTKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL30222818 | 0.75 | HTR1D (0.53) | HTR2CHTR1DHRH4ADRB2NCF1 | |
| SCHEMBL12224756 | 0.75 | HTR2C (0.50) | HTR2CHTR1DHRH4ADRB2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | HTR2C 947/4885HTR1D 640/4885HRH4 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.