⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382753 | 1.00 | — | — | |
| Formaldehyde SCHEMBL29240890 | 0.93 | FDFT1 (0.39) | — | |
| SCHEMBL2824810 | 0.82 | PDGFRB (0.40) | — | |
| SCHEMBL16345402 | 0.75 | MEN1 (0.44) | — | |
| SCHEMBL15522598 | 0.74 | MAP4K4 (0.40) | — | |
| SCHEMBL787481 | 0.73 | CYP19A1 (0.44) | — | |
| SCHEMBL29740319 | 0.73 | CYP19A1 (0.44) | — | |
| SCHEMBL10633324 | 0.73 | NR3C1 (0.41) | — | |
| SCHEMBL10627287 | 0.73 | NPC1 (0.62) | — | |
| SCHEMBL7880596 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3158 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4716683-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF A P2X3 INHIBITOR | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-01 | — | — | EP | claimed |
| US-12209086-B2 | FGFR3 inhibitor compounds | ELI LILLY AND COMPANY (US) | 2025-01-28 | — | — | US | claimed |
| WO-2024240728-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF A P2X3 INHIBITOR | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-11-28 | — | — | WO | claimed |
| US-20240190870-A1 | FGFR3 INHIBITOR COMPOUNDS | LOXO ONCOLOGY, INC. | 2024-06-13 | — | — | US | claimed |
| CN-116510644-A | Synthesis method of trifluoromethyl substituted fluorine-containing heterocyclic formic acid | 烟台宁远药业有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-114773391-A | Fluorine-containing transition metal complex, preparation method and application thereof | 联碳新材料技术(杭州)有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-106117134-A | The synthetic method of medical material 5-fluoro-2-bromine isonicotinic acid | 无锡乾浩生物医药有限公司 | 2016-11-16 | — | — | CN | claimed |
| WO-2008054284-A1 | A NEW PROCESS FOR THE PRODUCTION OF 5-FLUORO-PYRIDINE-2- CARBONITRILE AND 5-FLUORO-N-HYDROXY-PYRIDINE-2- CARBOXAMIDINE. | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | claimed |
| CN-122079985-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079984-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079983-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| US-12637451-B2 | Amino quinazoline derivatives as P2X3 inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-05-26 | — | — | US | disclosed |
| WO-2026106499-A1 | OREXIN RECEPTOR ANTAGONISTS: 2-AZABICYCLIC COMPOUNDS | BIAL - PORTELA & CA., S.A. (PT) | 2026-05-21 | — | — | WO | disclosed |
| CN-115650982-B | Compounds for imaging TAU protein aggregates | AC免疫有限公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-2002038568-A1 | IMIDAZO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-05-16 | — | — | WO | disclosed |
| WO-2002010154-A2 | SUBSTITUTED HETEROCYCLIC AMIDES | ELI LILLY AND COMPANY (US) | 2002-02-07 | — | — | WO | disclosed |
| US-4457927-A | Pyrido[2,1-b]quinazolinone derivatives and the preparation and use thereof | SCHERING, AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0011142-B1 | PYRIDO (2,1-B) QUINAZOLINONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |
| EP-0011142-A1 | Pyrido (2,1-b) quinazolinones, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |
| US-3947457-A | Method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines | THE DOW CHEMICAL COMPANY (US) | 1976-03-30 | — | — | US | disclosed |