Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928800 | 0.94 | TSHR (0.54) | TSHRTDP1USP2RAB9AKMT2A | |
| SCHEMBL1023779 | 0.93 | TSHR (0.56) | TSHRTDP1USP2EPHX1RAB9A | |
| SCHEMBL1021522 | 0.88 | TSHR (0.58) | TSHRTDP1KMT2AMEN1POLB | |
| SCHEMBL989495 | 0.88 | TSHR (0.58) | TSHRTDP1USP2EPHX1RAB9A | |
| SCHEMBL1022340 | 0.88 | TSHR (0.60) | TSHRTDP1L3MBTL1GAANPSR1 | |
| SCHEMBL1954170 | 0.87 | TSHR (0.55) | TSHRTDP1USP2EPHX1RAB9A | |
| SCHEMBL29914175 | 0.87 | TSHR (0.55) | TSHRTDP1USP2EPHX1RAB9A | |
| SCHEMBL2932515 | 0.86 | TSHR (0.51) | TSHRTDP1USP2RAB9AKMT2A | |
| SCHEMBL1838093 | 0.85 | TSHR (0.57) | TSHRTDP1 | |
| SCHEMBL990592 | 0.83 | TSHR (0.55) | TSHRTDP1USP2EPHX1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |