Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926648 | 0.94 | TSHR (0.53) | TSHRTDP1MEN1KMT2APOLB | |
| SCHEMBL1023557 | 0.89 | TSHR (0.55) | TSHRTDP1 | |
| SCHEMBL1022247 | 0.88 | TSHR (0.59) | TSHRTDP1MEN1KMT2APOLB | |
| SCHEMBL1021773 | 0.86 | TSHR (0.55) | TSHRTDP1MEN1KMT2APOLB | |
| SCHEMBL2926650 | 0.83 | TSHR (0.40) | TSHR | |
| SCHEMBL1023779 | 0.83 | TSHR (0.56) | TSHRTDP1GAA | |
| SCHEMBL2928103 | 0.83 | TSHR (0.50) | TSHRTDP1GAA | |
| SCHEMBL1021679 | 0.82 | TSHR (0.60) | TSHRTDP1MEN1KMT2APOLB | |
| SCHEMBL2928800 | 0.82 | TSHR (0.54) | TSHRTDP1MEN1KMT2APOLB | |
| SCHEMBL2948074 | 0.81 | TSHR (0.50) | TSHRTDP1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |