Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684731 | 0.89 | CTSK (0.51) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL29231873 | 0.88 | PPARG (0.50) | LMNAMAPTCTSKCTSSPPARA | |
| SCHEMBL2982543 | 0.88 | CTSK (0.41) | CTSKCTSSPPARAPPARGSYK | |
| SCHEMBL30192895 | 0.88 | PPARG (0.50) | LMNAMAPTCTSKCTSSPPARA | |
| SCHEMBL24876544 | 0.88 | CTSK (0.46) | CTSKCTSSPPARAPPARGPPARD | |
| SCHEMBL25447128 | 0.84 | PPARG (0.53) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL3935723 | 0.84 | PPARG (0.53) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL7742068 | 0.83 | HPGD (0.42) | LMNACTSKCTSS | |
| SCHEMBL2573117 | 0.82 | CTSK (0.45) | CTSKCTSSPPARAPPARGMIF | |
| SCHEMBL1022960 | 0.82 | CXCR2 (0.45) | ESR1CTSKCTSSPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478619-B1 | A PROCESS FOR PREPARING A PHENYLALANINE DERIVATIVE AND INTERMEDIATES THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-01-12 | — | — | EP | disclosed |