Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939418 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL1933484 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL984789 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL12699925 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL24192388 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL1573970 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL1517596 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL1933186 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KMT2ACA2CA12CA9 | |
| SCHEMBL1932741 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2ACA2CA1CA12 | |
| SCHEMBL1932739 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2ACA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524947-B2 | Acylsulfonamides and processes for producing the same | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524947-B2 | Acylsulfonamides and processes for producing the same | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-09-03 | — | — | US | disclosed |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2012021486-A2 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-16 | — | — | WO | disclosed |
| US-20110130568-A1 | Acylsulfonamides and Processes for Producing the Same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-02 | — | — | US | disclosed |
| US-20110130568-A1 | Acylsulfonamides and Processes for Producing the Same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-02 | — | — | US | disclosed |
| WO-2009105751-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130568-A1 | Acylsulfonamides and Processes for Producing the Same | BCL2, BCL2L2, BCL6 | ALDH1A1 3847/4885KMT2A 1022/4885CA2 1346/4885 |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | BCL2, BCL2L2, BCL6 | ALDH1A1 3847/4885KMT2A 1022/4885CA2 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.