Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 3/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056439 | 1.00 | SLC1A2 (0.37) | SLC1A2ARG1ARG2 | |
| SCHEMBL12943747 | 0.75 | SLC1A2 (0.37) | SLC1A2ARG1ARG2 | |
| SCHEMBL942836 | 0.75 | SLC1A2 (0.37) | SLC1A2ARG1ARG2 | |
| SCHEMBL15121802 | 0.75 | SLC1A2 (0.37) | SLC1A2ARG1ARG2 | |
| SCHEMBL15121803 | 0.75 | SLC1A2 (0.37) | SLC1A2ARG1ARG2 | |
| SCHEMBL1056777 | 0.72 | FUCA1 (0.38) | SLC1A2ARG1ARG2 | |
| SCHEMBL1074893 | 0.72 | FUCA1 (0.38) | SLC1A2ARG1ARG2 | |
| SCHEMBL10419707 | 0.69 | ARG1 (0.44) | SLC1A2ARG1 | |
| SCHEMBL19504964 | 0.69 | — | — | |
| SCHEMBL31085639 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448946-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | Novartis AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011000855-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | NOVARTIS AG (CH) | 2011-01-06 | — | — | WO | disclosed |