Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.43 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.41 |
| ▸ | CTRL | P40313 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.41 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.41 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836101 | 0.91 | SIGMAR1 (0.47) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL3836098 | 0.91 | SIGMAR1 (0.47) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL1030781 | 0.88 | SIGMAR1 (0.48) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL12883690 | 0.86 | SIGMAR1 (0.51) | SIGMAR1FOLH1 | |
| SCHEMBL1030777 | 0.81 | BIRC2 (0.48) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL13647325 | 0.81 | BIRC2 (0.48) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL1177237 | 0.81 | SIGMAR1 (0.45) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL1030783 | 0.81 | BIRC2 (0.48) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL3838521 | 0.79 | PSMB5 (0.40) | SIGMAR1PSMB5PSMB10PSMB2PSMB8 | |
| SCHEMBL21793572 | 0.78 | TMPRSS11D (0.65) | PSMB5PSMB10PSMB2PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274621-A2 | COMPOUNDS AND METHODS FOR THE LABELING AND AFFINITY-SELECTION OF PROTEINS | Koninklijke Philips Electronics N.V. (NL) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009125316-A2 | COMPOUNDS AND METHODS FOR THE LABELING AND AFFINITY-SELECTION OF PROTEINACEOUS MOLECULES | KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) | 2009-10-15 | — | — | WO | disclosed |