⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188324 | 0.86 | — | — | |
| SCHEMBL9518949 | 0.86 | — | — | |
| SCHEMBL11688591 | 0.84 | HDAC3 (0.44) | — | |
| SCHEMBL302492 | 0.84 | — | — | |
| SCHEMBL270308 | 0.81 | — | — | |
| SCHEMBL19212465 | 0.80 | GPR84 (0.55) | — | |
| SCHEMBL10541073 | 0.75 | CES1 (0.50) | — | |
| SCHEMBL1200789 | 0.73 | — | — | |
| SCHEMBL42275 | 0.73 | — | — | |
| SCHEMBL3402330 | 0.73 | HDAC3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220223-A1 | Novel human NK3 receptor-selective antagonist compounds, method for obtaining them and pharmaceutical compositions containing them | SANOFI-AVENTIS (FR) | 2004-11-04 | — | — | US | claimed |
| US-20020049329-A1 | Novel human NK3 receptor-selective antagonist compounds, method for obtaining them and pharmaceutical compositions containing them | SANOFI-AVENTIS (FR) | 2002-04-25 | — | — | US | claimed |
| US-6291672-B1 | FOR THE PREPARATION OF DRUGS USEFUL IN THERAPY OF PSYCHIATRIC DISEASES, DISEASES OF PSYCHOSOMATIC ORIGIN, HYPERTENSION | SANOFI-SYNTHELABO (FR) | 2001-09-18 | — | — | US | claimed |
| US-6028082-A | FOR TRATING PSYCHOLOGICAL DISORDERS | SANOFI-SYNTHELABO (FR) | 2000-02-22 | — | — | US | claimed |
| EP-0625509-B1 | N-alkyl substituted piperidine-derivatives with neurokinin receptor antagonist activity | ZENECA LTD (GB) | 1997-07-30 | — | — | EP | claimed |
| US-5521199-A | TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | claimed |
| EP-0625509-A1 | N-alkyl substituted piperidine-derivatives with neurokinin receptor antagonist activity | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | claimed |
| EP-3492104-B1 | USE OF 10H-BENZO [G] PTERIDIN-2,4-DION DERIVATIVES | TRIOPTOTEC GMBH (DE) | 2023-02-15 | — | — | EP | disclosed |
| CN-110799345-B | Tamper-resistant media for thermal printing | 欧米亚国际集团 | 2022-04-19 | — | — | CN | disclosed |
| EP-3838902-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE OF SAME | TriOptoTec GmbH (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-2723743-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2019-08-14 | — | — | EP | disclosed |
| EP-3135110-B1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | TRIOPTOTEC GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-3492104-A1 | USE OF 10H-BENZO [G] PTERIDIN-2,4-DION DERIVATIVES | Trioptotec GmbH (DE) | 2019-06-05 | — | — | EP | disclosed |
| EP-0625509-B1 | N-alkyl substituted piperidine-derivatives with neurokinin receptor antagonist activity | ZENECA LTD (GB) | 1997-07-30 | — | — | EP | disclosed |
| EP-0463400-B1 | Transparencies | XEROX CORP (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5521199-A | TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0625509-A1 | N-alkyl substituted piperidine-derivatives with neurokinin receptor antagonist activity | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |
| US-5202205-A | TRANSPARENCIES COMPRISING METAL HALIDE OR UREA ANTISTATIC LAYER | XEROX CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0463400-A1 | Transparencies | XEROX CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4251507-A | USING CELLULOSIC COMPOUNDS | DOMINION PHARMACAL, INC. (US) | 1981-02-17 | — | — | US | disclosed |