⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022936 | 1.00 | — | — | |
| SCHEMBL6560379 | 0.84 | — | — | |
| SCHEMBL3314586 | 0.84 | — | — | |
| SCHEMBL3314587 | 0.84 | — | — | |
| Water SCHEMBL271474 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11374338 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11374337 | 0.82 | — | — | |
| SCHEMBL6751259 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL6751262 | 0.80 | TSHR (0.39) | — | |
| Water SCHEMBL5877932 | 0.80 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830913-A | Method for preparing 2, 5-furan diformylaldoxime | 中国科学院宁波材料技术与工程研究所 | 2021-05-25 | — | — | CN | disclosed |
| US-8013187-B2 | 2-cyclopenten-1-one oxime derivatives inhibiting production of TNF-α | AMOREPACIFIC CORPORATION (KR) | 2011-09-06 | — | — | US | disclosed |
| US-8013187-B2 | 2-cyclopenten-1-one oxime derivatives inhibiting production of TNF-α | AMOREPACIFIC CORPORATION (KR) | 2011-09-06 | — | — | US | disclosed |
| US-8013187-B2 | 2-cyclopenten-1-one oxime derivatives inhibiting production of TNF-α | AMOREPACIFIC CORPORATION (KR) | 2011-09-06 | — | — | US | disclosed |
| CN-101068774-B | 2-cyclopenten-1-one oxime derivatives inhibiting production of TNF-alpha | AMOREPACIFIC CORP | 2011-08-10 | — | — | CN | disclosed |
| CN-101068774-B | 2-cyclopenten-1-one oxime derivatives inhibiting production of TNF-alpha | AMOREPACIFIC CORP | 2011-08-10 | — | — | CN | disclosed |
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | disclosed |
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009072808-A3 | COSMETIC COMPOSITION FOR BODY SLIMMING CONTAINING 2-CYCLOPENTENE-1-ONE OXIME DERIVATIVES | AMOREPACIFIC CORP (KR) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009072808-A2 | COSMETIC COMPOSITION FOR BODY SLIMMING CONTAINING 2-CYCLOPENTENE-1-ONE OXIME DERIVATIVES | AMOREPACIFIC CORPORATION (KR) | 2009-06-11 | — | — | WO | disclosed |
| EP-1841729-A1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | Amorepacific Corporation (KR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006059867-A1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORPORATION (KR) | 2006-06-08 | — | — | WO | disclosed |
| US-6706153-B2 | DISTILLATION | DSM N.V. (NL) | 2004-03-16 | — | — | US | disclosed |
| US-20020005343-A1 | PROCESS FOR THE SEPARATION OF A KETOXIME OR ALDOXIME FROM AN AMIDE | DSM IP ASSETS B.V. (NL) | 2002-01-17 | — | — | US | disclosed |
| EP-0931061-A1 | PROCESS FOR THE SEPARATION OF A KETOXIME OR ALDOXIME FROM AN AMIDE | DSM N.V. (NL) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998002416-A1 | PROCESS FOR THE SEPARATION OF A KETOXIME OR ALDOXIME FROM AN AMIDE | DSM N.V. (NL) | 1998-01-22 | — | — | WO | disclosed |
| EP-0577203-B1 | Process for the conversion of oximes into the corresponding amides | DSM NV (NL) | 1997-01-22 | — | — | EP | disclosed |
| EP-0595364-B1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-07-24 | — | — | EP | disclosed |
| EP-0577203-A1 | Process for the conversion of oximes into the corresponding amides | DSM N.V. (NL) | 1994-01-05 | — | — | EP | disclosed |
| US-4472192-A | POST-AND PREEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1984-09-18 | — | — | US | disclosed |