SCHEMBL1023055

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12774267	0.90	BRAF (0.56)	P2RX1IL2BRAFJAK2JAK1
	SCHEMBL1024652	0.88	MEN1 (0.57)	MEN1KMT2AP2RX1TMPRSS4AKT1
	SCHEMBL1025872	0.86	MEN1 (0.56)	MEN1KMT2AP2RX1TMPRSS4AKT1
	SCHEMBL1025021	0.86	TMPRSS4 (0.57)	MEN1KMT2AP2RX1TMPRSS4AKT1
	SCHEMBL1027417	0.85	TMPRSS4 (0.56)	MEN1KMT2AP2RX1TMPRSS4AKT1
	SCHEMBL1024009	0.85	MEN1 (0.55)	MEN1KMT2AP2RX1TMPRSS4AKT1
	SCHEMBL1023074	0.84	P2RX1 (0.50)	KMT2AP2RX1TMPRSS4IL2BRAF
	SCHEMBL12708574	0.83	P2RX1 (0.48)	KMT2AP2RX1IL2BRAFJAK2
	SCHEMBL1024429	0.82	P2RX1 (0.48)	MEN1KMT2AP2RX1TMPRSS4AKT1
	SCHEMBL12708535	0.81	BRAF (0.55)	P2RX1IL2BRAFJAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.