Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114204 | 0.90 | MAPT (0.47) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL3604196 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL3604193 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL103405 | 0.85 | KMT2A (0.46) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL30006357 | 0.85 | SMARCA2 (0.48) | MAPTGAAALDH1A1SMN1; SMN2SMARCA2 | |
| SCHEMBL102545 | 0.85 | MAPT (0.60) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL31615706 | 0.85 | MAPT (0.60) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL105500 | 0.84 | SMARCA2 (0.55) | MAPTGAAALDH1A1SMN1; SMN2SMARCA2 | |
| SCHEMBL28028630 | 0.83 | MEN1 (0.51) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL3957603 | 0.83 | SMARCA2 (0.53) | MAPTALDH1A1SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |