Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4848974 | 0.99 | HTT (0.46) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL1024723 | 0.82 | CPB1 (0.47) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| Acetic Acid SCHEMBL4856558 | 0.81 | CPB1 (0.46) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL1024008 | 0.79 | KMT2A (0.48) | — | |
| Hydrochloric Acid SCHEMBL4883005 | 0.79 | HTT (0.48) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL1024168 | 0.78 | MAPT (0.51) | FOLH1 | |
| SCHEMBL19384905 | 0.75 | HTT (0.64) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL615296 | 0.75 | HTT (0.72) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL14010427 | 0.75 | HTT (0.63) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| Acetic Acid SCHEMBL4881411 | 0.74 | CPB1 (0.52) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797110-B1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO KG (DE) | 2011-01-12 | — | — | EP | disclosed |