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CPB1

Carboxypeptidase B · P15086 · CPB1 on Sugi Atlas →

18,865 patent compounds predicted against CPB1, 11,215 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1441194 SCHEMBL1441194 0.40 5/20
SCHEMBL589342 SCHEMBL589342 0.38 5/20
SCHEMBL710279 SCHEMBL710279 0.46 4/20
SCHEMBL1702282 SCHEMBL1702282 0.35 4/20
SCHEMBL408085 SCHEMBL408085 0.47 3/20
SCHEMBL479855 SCHEMBL479855 0.42 3/20
SCHEMBL653643 SCHEMBL653643 0.40 3/20
SCHEMBL1698763 SCHEMBL1698763 0.36 3/20
SCHEMBL867807 SCHEMBL867807 0.33 3/20
N-Methylhistamine N-Methylhistamine (SCHEMBL1320841) 0.31 3/20
SCHEMBL579214 SCHEMBL579214 0.72 2/20
SCHEMBL709146 SCHEMBL709146 0.68 2/20
SCHEMBL706633 SCHEMBL706633 0.62 2/20
SCHEMBL709053 SCHEMBL709053 0.62 2/20
SCHEMBL704705 SCHEMBL704705 0.61 2/20
SCHEMBL394782 SCHEMBL394782 0.60 2/20
SCHEMBL394783 SCHEMBL394783 0.60 2/20
SCHEMBL395240 SCHEMBL395240 0.60 2/20
SCHEMBL714564 SCHEMBL714564 0.60 2/20
SCHEMBL715267 SCHEMBL715267 0.60 2/20

Clinical trials — most relevant to CPB1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Pilot Study Comparing Anti-Inflammatory Effects Of TXA Versus EACA In Pediatric Congenital Heart Surgery PHASE4COMPLETED
Bradykinin Receptor Antagonism During Cardiopulmonary Bypass PHASE2/PHASE3COMPLETED
Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery PHASE1/PHASE2UNKNOWN
Precision Medicine in the CICU: Identifying Proteomic Biomarkers nanENROLLING_BY_INVITATION
Acute Pancreatitis Targets (APT) Study nanCOMPLETED
Evaluation of Plasma Renin Concentrations in Cardiac Surgery nanRECRUITING
Inflammation Markers Over Time in Cardiovascular Disease nanCOMPLETED
Markers in Acute Pancreatitis-1 nanCOMPLETED
Aprotinin Use and Renal Outcome in Hypothermic Bypass and Circulatory Arrest for Surgical Repair of Thoracic Aorta. nanCOMPLETED
Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury nanCOMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations nanCOMPLETED
Disorders of the Acute Phase Response Following Trauma and Invasive Surgery nanENROLLING_BY_INVITATION
Clinical Assessment of Thrombosis in Children After Heart Surgery nanCOMPLETED
Catalytic Antibodies to Predict Uninvasively Late Transplant Failure nanCOMPLETED
Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin nanCOMPLETED
Protein Digestion and Amino Acid Absorption in the Aging Gastrointestinal Tract nanCOMPLETED
Surfactant Derived Protocol in Heart Failure nanCOMPLETED
Delirium in Elderly Undergoing Cardiac Surgery and the Significance of CholinEsterase Activity nanCOMPLETED
The Prospective Risk Factor Evaluation & Discovery In CTEPH Study nanUNKNOWN
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3 nanCOMPLETED
NAG-excretion During Cardiopulmonary Bypass nanCOMPLETED
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED
The Role of Pentraxin 3 and Cathepsin B Levels in Preeclamptic Pregnancy nanCOMPLETED
Osteopontin Gene Polymorphism in Stroke Patients in Egypt nanNOT_YET_RECRUITING
Heparin Responses in Pediatric Patients Undergoing Cardiopulmonary Bypass. nanCOMPLETED
The Influence of NPPA/NPPB Haplotype on Natriuretic Peptide Plasma Levels nanCOMPLETED
Identification of Heritable CTEPH nanUNKNOWN
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Thrombin Generation in Neonates nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CPB1 binder may also engage these)

ProteinNameSimilarity
P09955 — 1.000 P09955 →
P19223 — 1.000 P19223 →
P00732 — 1.000 P00732 →
P55261 — 1.000 P55261 →
CPA2 Carboxypeptidase A2 0.999 landscape →
P09954 — 0.998 P09954 →
P00731 — 0.997 P00731 →
CPA1 Carboxypeptidase A1 0.997 landscape →
P00730 — 0.996 P00730 →
Q29NC4 — 0.996 Q29NC4 →
Q504N0 — 0.995 Q504N0 →
Q7TPZ8 — 0.995 Q7TPZ8 →
CPA4 Carboxypeptidase A4 0.994 landscape →
Q8WXQ8 — 0.994 Q8WXQ8 →
A0A1S4F020 — 0.993 A0A1S4F020 →
P19222 — 0.993 P19222 →
Q6P8K8 — 0.993 Q6P8K8 →
Q9VL86 — 0.992 Q9VL86 →
O02350 — 0.992 O02350 →
Q9EQV9 — 0.992 Q9EQV9 →
B8XGR3 — 0.990 B8XGR3 →
Q3T905 — 0.990 Q3T905 →
C5FVN6 — 0.989 C5FVN6 →
Q2KIG3 — 0.989 Q2KIG3 →
D4DL57 — 0.989 D4DL57 →
D4D675 — 0.988 D4D675 →
B6V865 — 0.988 B6V865 →
Q8R4H4 — 0.988 Q8R4H4 →
Q9JHH6 — 0.987 Q9JHH6 →
Q4R7R2 — 0.987 Q4R7R2 →