⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65108 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7285171 | 0.69 | — | — | |
| SCHEMBL4616815 | 0.67 | — | — | |
| SCHEMBL633202 | 0.67 | — | — | |
| SCHEMBL20355954 | 0.67 | — | — | |
| Bromide SCHEMBL8068623 | 0.67 | — | — | |
| SCHEMBL3272627 | 0.67 | — | — | |
| SCHEMBL12777891 | 0.67 | — | — | |
| SCHEMBL19059659 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL6247431 | 0.65 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109643752-A | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | 西北大学 | 2019-04-16 | — | — | CN | claimed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| US-20250179061-A1 | RIP1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2025-06-05 | — | — | US | disclosed |
| CN-116113635-B | Spiro compounds as melanocortin 4 receptor antagonists and uses thereof | 辉瑞公司 | 2025-03-18 | — | — | CN | disclosed |
| US-20250084084-A1 | Crystalline form of (2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3-pyrrolidin]-1-yl]propan-1-one | PFIZER INC. (US) | 2025-03-13 | — | — | US | disclosed |
| EP-4486743-A1 | RIP1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-01-08 | — | — | EP | disclosed |
| US-20240400534-A1 | CHEMICAL TOOLS FOR DRUG TARGET IDENTIFICATION AND CHARACTERIZATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-12-05 | — | — | US | disclosed |
| EP-4161927-B9 | SPIRO COMPOUNDS AS MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER (US) | 2024-11-06 | — | — | EP | disclosed |
| CN-118765280-A | RIP1 modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-10-11 | — | — | CN | disclosed |
| EP-4161927-B1 | SPIRO COMPOUNDS AS MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER (US) | 2024-08-07 | — | — | EP | disclosed |
| WO-2004080998-A1 | IMIDAZOL-4-YL-ETHYNYL-PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-23 | — | — | WO | disclosed |
| EP-0242973-B1 | INDOLE DERIVATIVES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1991-07-17 | — | — | EP | disclosed |
| US-4900839-A | SUBSTITUTED PHENYLPROPENAMIDES | PFIZER INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4837334-A | Precursors to quinolone inotropic agents | PFIZER INC. (US) | 1989-06-06 | — | — | US | disclosed |
| US-4808581-A | ANXIOLYTIC, ANTIEMETIC, TREATMENT OF PSYCHOLOGICAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1989-02-28 | — | — | US | disclosed |
| US-4740513-A | CARDIAC STIMULANTS | PFIZER INC. (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0257918-A1 | Quinolone cardiac stimulants | Pfizer Limited (GB) | 1988-03-02 | — | — | EP | disclosed |
| US-4728653-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0242973-A1 | Indole derivatives, method for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1987-10-28 | — | — | EP | disclosed |
| EP-0226357-A1 | Quinolone cardiac stimulants | Pfizer Limited (GB) | 1987-06-24 | — | — | EP | disclosed |