SCHEMBL1023752

SCHEMBL1023752

CC(C)(C)[Si](C)(C)OCCCN(C#N)c1ccc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.63
F2 P00734 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023288 0.96 F10 (0.65) F10F2
SCHEMBL1023879 0.85 F10 (0.75) F10F2
SCHEMBL4963060 0.84 F10 (0.63) F10F2
SCHEMBL1022331 0.83 F10 (0.71) F10F2
SCHEMBL87217 0.78 F10 (1.00) F10F2
SCHEMBL1001747 0.77 F10 (0.40) F10
SCHEMBL78024 0.77 F10 (1.00) F10F2
SCHEMBL4276725 0.77 F10 (0.76) F10F2
SCHEMBL77887 0.76 F10 (0.84) F10F2
SCHEMBL15247387 0.76 F10 (0.80) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945634-B1 PHENYLENEBISOXAZOLIDINE DERIVATIVES AND THEIR USE AS ANTICOAGULANTS BAYER SCHERING PHARMA AG (DE) 2011-01-19 EP disclosed
US-20100041646-A1 Phenylene-Bis-Oxazolidine Derivatives and Their Use as Anticoagulants BAYER HEALTHCARE AG (DE) 2010-02-18 US disclosed
US-20100041646-A1 Phenylene-Bis-Oxazolidine Derivatives and Their Use as Anticoagulants BAYER HEALTHCARE AG (DE) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041646-A1 Phenylene-Bis-Oxazolidine Derivatives and Their Use as Anticoagulants SELP, SERPINC1, F2 F10 346/4885F2 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.