Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | USP14 | P54578 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15168942 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HRH3HRH2HRH1KCNH2 | |
| SCHEMBL15179505 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HRH3HRH2HRH1KCNH2 | |
| Hydrochloric Acid SCHEMBL15168947 | 0.99 | ALDH1A1 (0.46) | ALDH1A1HRH3HRH2HRH1KCNH2 | |
| SCHEMBL15168555 | 0.83 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL15169260 | 0.83 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL15169761 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HRH3HRH2HRH1USP14 | |
| SCHEMBL15169759 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HRH3HRH2HRH1USP14 | |
| SCHEMBL17452474 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HRH3 | |
| SCHEMBL324417 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HRH3 | |
| SCHEMBL324137 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004604-A1 | TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Convergence Pharmaceuticals Limited (GB) | 2012-01-12 | — | — | WO | disclosed |