Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 7/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16199556 | 0.84 | AR (0.39) | AR | |
| SCHEMBL19309328 | 0.81 | SOS1 (0.33) | LRRK2AR | |
| SCHEMBL15179472 | 0.81 | SOS1 (0.33) | LRRK2AR | |
| SCHEMBL16192660 | 0.81 | SOS1 (0.33) | LRRK2AR | |
| Hydrochloric Acid SCHEMBL15168435 | 0.80 | SOS1 (0.32) | LRRK2AR | |
| Hydrochloric Acid SCHEMBL15168430 | 0.80 | SOS1 (0.32) | LRRK2AR | |
| SCHEMBL10239290 | 0.79 | ALDH1A1 (0.45) | LRRK2ALDH1A1ARGRM2 | |
| Hydrochloric Acid SCHEMBL15168481 | 0.78 | ALDH1A1 (0.44) | LRRK2ALDH1A1ARGRM2 | |
| Hydrochloric Acid SCHEMBL16192638 | 0.76 | AR (0.31) | LRRK2AR | |
| SCHEMBL10239643 | 0.76 | ALDH1A1 (0.40) | LRRK2ALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004604-A1 | TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Convergence Pharmaceuticals Limited (GB) | 2012-01-12 | — | — | WO | disclosed |