Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720887 | 0.90 | RECQL (0.63) | SMN1; SMN2HPGDMEN1KMT2AGAA | |
| SCHEMBL10330514 | 0.84 | HTT (0.65) | SMN1; SMN2HPGDKMT2AGAARECQL | |
| SCHEMBL3455477 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDKDM4EKMT2AGAA | |
| SCHEMBL13503962 | 0.82 | KDM4E (0.84) | SMN1; SMN2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL25432112 | 0.80 | TSHR (0.70) | SMN1; SMN2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10396663 | 0.80 | HPGD (0.74) | SMN1; SMN2HPGDKDM4EMEN1KMT2A | |
| SCHEMBL24016862 | 0.80 | LMNA (0.54) | SMN1; SMN2HPGDMEN1KMT2ARECQL | |
| SCHEMBL18801768 | 0.80 | LMNA (0.54) | SMN1; SMN2HPGDMEN1KMT2ARECQL | |
| SCHEMBL30334082 | 0.79 | MEN1 (0.61) | KDM4EMEN1KMT2ATSHRHTT | |
| SCHEMBL18166095 | 0.79 | RECQL (0.75) | SMN1; SMN2HPGDMEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058127-A2 | NOVEL COMPOUNDS THAT ARE ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-05-03 | — | — | WO | disclosed |