SCHEMBL10240641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10241927	0.93	CYP3A4 (0.50)	MEN1KMT2APOLBKDM4EADCY1
	SCHEMBL10241886	0.90	CYP3A4 (0.56)	MEN1KMT2AADCY1RAB9ANPC1
	SCHEMBL10241942	0.89	CYP3A4 (0.51)	RXFP1MEN1KMT2APOLBRAB9A
	SCHEMBL10240630	0.89	CYP3A4 (0.49)	MEN1KMT2AADCY1NPC1CYP3A4
	SCHEMBL10240281	0.87	CYP2C8 (0.57)	ADCY1CYP3A4CYP2C8KCNH2
	SCHEMBL10241932	0.86	CYP3A4 (0.47)	KDM4ECYP3A4CYP2C8KCNH2ALDH1A1
	SCHEMBL10241770	0.86	SIRT2 (0.55)	RXFP1MEN1KMT2AKDM4EADCY1
	SCHEMBL10241990	0.85	ROCK2 (0.49)	CYP3A4CYP2C8KCNH2
	SCHEMBL1918709	0.85	CYP2C8 (0.56)	MEN1KMT2AKDM4EADCY1SMN1; SMN2
	SCHEMBL10280821	0.85	CYP3A4 (0.48)	CYP3A4CYP2C8KCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.