Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414772 | 1.00 | EGFR (0.35) | EGFRMETROS1ALKMEN1 | |
| SCHEMBL414771 | 1.00 | EGFR (0.35) | EGFRMETROS1ALKMEN1 | |
| SCHEMBL10204794 | 0.88 | KMT2A (0.36) | MEN1KMT2AGAAMAPTMAOB | |
| SCHEMBL416309 | 0.82 | MEN1 (0.40) | EGFRMETROS1ALKMEN1 | |
| SCHEMBL10240649 | 0.82 | MEN1 (0.40) | EGFRMETROS1ALKMEN1 | |
| SCHEMBL414779 | 0.82 | MEN1 (0.40) | EGFRMETROS1ALKMEN1 | |
| SCHEMBL414896 | 0.82 | ABL1 (0.41) | EGFRMETMEN1KMT2AGAA | |
| SCHEMBL414897 | 0.82 | ABL1 (0.41) | EGFRMETMEN1KMT2AGAA | |
| SCHEMBL10241398 | 0.82 | ABL1 (0.41) | EGFRMETMEN1KMT2AGAA | |
| SCHEMBL17851266 | 0.82 | HCRTR1 (0.37) | HCRTR1HCRTR2ABL1BCRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |