Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | BCR | P11274 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10241398 | 1.00 | ABL1 (0.41) | ABL1BCRLMNAMEN1KMT2A | |
| SCHEMBL414897 | 1.00 | ABL1 (0.41) | ABL1BCRLMNAMEN1KMT2A | |
| SCHEMBL432860 | 0.94 | ABL1 (0.39) | ABL1BCRLMNAMEN1KMT2A | |
| SCHEMBL432859 | 0.94 | ABL1 (0.39) | ABL1BCRLMNAMEN1KMT2A | |
| SCHEMBL10204790 | 0.88 | LMNA (0.42) | LMNAMEN1KMT2APIK3CAMTOR | |
| SCHEMBL10240649 | 0.85 | MEN1 (0.40) | LMNAMEN1KMT2ATRPV1GAA | |
| SCHEMBL416309 | 0.85 | MEN1 (0.40) | LMNAMEN1KMT2ATRPV1GAA | |
| SCHEMBL414779 | 0.85 | MEN1 (0.40) | LMNAMEN1KMT2ATRPV1GAA | |
| SCHEMBL8909899 | 0.82 | ABL1 (0.56) | ABL1BCRLMNAMEN1KMT2A | |
| SCHEMBL10241405 | 0.82 | EGFR (0.35) | ABL1BCRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | claimed |
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | claimed |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-10-10 | — | — | US | claimed |
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-06-13 | — | — | US | claimed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | claimed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | claimed |
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | disclosed |
| US-8785630-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-06-13 | — | — | US | disclosed |
| EP-2595965-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2013-05-29 | — | — | EP | disclosed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | ABL1 1509/4885BCR 2634/4885LMNA 4005/4885 |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | ABL1 1509/4885BCR 2634/4885LMNA 4005/4885 |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | ABL1 1509/4885BCR 2634/4885LMNA 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.