Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 16/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10241863 | 0.85 | ALOX5AP (0.46) | ALOX5APMAPTLMNAHSD11B1MAP4K4 | |
| SCHEMBL11993800 | 0.78 | MAP4K4 (0.43) | ALOX5APMAPTLMNAHSD11B1MAP4K4 | |
| SCHEMBL10241816 | 0.75 | ALOX5AP (0.47) | ALOX5APMAP4K4 | |
| SCHEMBL10241315 | 0.75 | ALOX5AP (0.36) | ALOX5APMAPTLMNAHSD11B1 | |
| SCHEMBL15143149 | 0.68 | ALOX5AP (0.52) | ALOX5APHSD11B1 | |
| SCHEMBL1951940 | 0.68 | MAPT (0.52) | ALOX5APMAPTLMNAMAP4K4KDM4E | |
| SCHEMBL1256178 | 0.67 | MAPT (0.70) | ALOX5APMAPTLMNAMAP4K4KDM4E | |
| SCHEMBL11993798 | 0.67 | MAP4K4 (0.44) | ALOX5APMAPTLMNAHSD11B1MAP4K4 | |
| SCHEMBL10241314 | 0.67 | MAP4K4 (0.53) | ALOX5APMAPTLMNAHSD11B1MAP4K4 | |
| SCHEMBL4859450 | 0.66 | MAP4K4 (0.56) | ALOX5APMAPTLMNAMAP4K4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027322-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |