Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18341183 | 1.00 | KMT2A (0.47) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL18341181 | 1.00 | KMT2A (0.47) | KMT2AMEN1LMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4856193 | 0.98 | KMT2A (0.46) | KMT2AMEN1LMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL20974172 | 0.98 | KMT2A (0.46) | KMT2AMEN1LMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL20974171 | 0.98 | KMT2A (0.46) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL2268145 | 0.86 | MEN1 (0.47) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL9012916 | 0.84 | MEN1 (0.49) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL1642165 | 0.83 | KMT2A (0.51) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL17101835 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL18783553 | 0.81 | MEN1 (0.43) | KMT2AMEN1LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797110-B1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO KG (DE) | 2011-01-12 | — | — | EP | disclosed |