Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765432 | 0.92 | MLNR (0.82) | MLNRGHSR | |
| SCHEMBL10150923 | 0.91 | MLNR (0.68) | MLNRGHSR | |
| SCHEMBL11982923 | 0.91 | MLNR (0.68) | MLNRGHSR | |
| SCHEMBL13392344 | 0.90 | MLNR (0.84) | MLNR | |
| SCHEMBL14037154 | 0.90 | MLNR (0.69) | MLNRGHSR | |
| SCHEMBL17081904 | 0.88 | MLNR (0.67) | MLNRGHSR | |
| SCHEMBL11982875 | 0.87 | MLNR (0.69) | MLNR | |
| SCHEMBL11982921 | 0.87 | MLNR (0.69) | MLNR | |
| SCHEMBL13392244 | 0.82 | MLNR (0.88) | MLNR | |
| SCHEMBL10150187 | 0.82 | MLNR (1.00) | MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029501-B2 | Method for making macrocycles | RIGEL PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012061408-A2 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS. INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-7452862-B2 | Conformationally-controlled biologically active macrocyclic small molecules as motilin antagonists or ghrelin agonists | TRANZYME PHARMA, INC. (CA) | 2008-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | EZR, SQLE, CBR3 | MLNR 2024/4885GHSR 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.