Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242214 | 0.92 | MLNR (0.69) | MLNRGHSR | |
| SCHEMBL10150187 | 0.90 | MLNR (1.00) | MLNR | |
| SCHEMBL11982921 | 0.89 | MLNR (0.69) | MLNR | |
| SCHEMBL11982875 | 0.89 | MLNR (0.69) | MLNR | |
| SCHEMBL17081904 | 0.89 | MLNR (0.67) | MLNRGHSR | |
| SCHEMBL13392244 | 0.83 | MLNR (0.88) | MLNR | |
| SCHEMBL13392456 | 0.83 | MLNR (1.00) | MLNR | |
| SCHEMBL13696717 | 0.82 | MLNR (0.69) | MLNRGHSR | |
| SCHEMBL75370 | 0.82 | MLNR (0.85) | MLNR | |
| SCHEMBL13010990 | 0.82 | MLNR (0.62) | MLNRGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133235-B2 | Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders | OCERA THERAPEUTICS, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2431380-A2 | Macrocyclic antagonist of the motilin receptor for treatment of gastrointestinal dysmotility disorders | Tranzyme Pharma, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |