Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.63 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42558 | 0.96 | PTPN1 (0.71) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL8296637 | 0.95 | PTPN1 (0.74) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL14734057 | 0.92 | KMT2A (0.78) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| Hydrochloric Acid SCHEMBL5794594 | 0.91 | KMT2A (0.76) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL27840833 | 0.87 | KMT2A (0.71) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| Formamide SCHEMBL18488991 | 0.84 | KMT2A (0.68) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL4677815 | 0.84 | KMT2A (0.63) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL4677821 | 0.84 | KMT2A (0.63) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL28656982 | 0.84 | PTPN1 (0.89) | KMT2APTPN1RAB9ANPC1ENPP3 | |
| SCHEMBL125695 | 0.84 | PTPN1 (0.89) | KMT2APTPN1RAB9ANPC1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344287-B | Novel substituted biaryl compounds as indoleamine 2, 3-dioxygenase (IDO) inhibitors | 默沙东有限责任公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20190241533-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FORMA THERAPEUTICS, INC. | 2019-08-08 | — | — | US | disclosed |
| WO-2013028670-A1 | 2-SPIRO-SUBSTITUTED IMINOTHIAZINES AND THEIR MONO-AND DIOXIDES AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| EP-2409704-A2 | c-Met modulators and methods of use | Exelixis Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241533-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FASN, FABP1, SCD | KMT2A 4741/4885PTPN1 4255/4885RAB9A 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.