Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42558 | 0.98 | PTPN1 (0.71) | PTPN1RAB9ANPC1HPGDENPP3 | |
| SCHEMBL10242579 | 0.95 | KMT2A (0.69) | PTPN1RAB9ANPC1HPGDENPP3 | |
| SCHEMBL14734057 | 0.91 | KMT2A (0.78) | PTPN1RAB9ANPC1ENPP3ENPP1 | |
| SCHEMBL28656982 | 0.91 | PTPN1 (0.89) | PTPN1RAB9ANPC1HPGDENPP3 | |
| SCHEMBL125695 | 0.91 | PTPN1 (0.89) | PTPN1RAB9ANPC1HPGDENPP3 | |
| Hydrochloric Acid SCHEMBL5794594 | 0.89 | KMT2A (0.76) | PTPN1RAB9ANPC1ENPP3ENPP1 | |
| SCHEMBL27840833 | 0.86 | KMT2A (0.71) | PTPN1RAB9ANPC1ENPP3ENPP1 | |
| SCHEMBL9851155 | 0.84 | PTPN1 (0.77) | PTPN1RAB9ANPC1HPGDENPP3 | |
| SCHEMBL29057710 | 0.84 | PTPN1 (0.77) | PTPN1RAB9ANPC1HPGDENPP3 | |
| Formamide SCHEMBL18488991 | 0.83 | KMT2A (0.68) | PTPN1RAB9ANPC1ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213255-A | Synthetic method of six-membered ring benzylamine compound | 上海泰坦科技股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| EP-3215142-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2021-03-24 | — | — | EP | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |