Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 12/20 | 0.54 |
| ▸ | CDK9 | P50750 | 7/20 | 0.54 |
| ▸ | CCNK | O75909 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12565971 | 0.90 | CCNT1 (0.67) | CCNT1CDK9CCNK | |
| SCHEMBL12812140 | 0.89 | CCNT1 (0.51) | CCNT1CDK9CCNKCNR2ABL1 | |
| SCHEMBL10242714 | 0.88 | CDK9 (0.50) | CCNT1CDK9CCNKCNR2 | |
| SCHEMBL10241724 | 0.87 | CDK9 (0.61) | CCNT1CDK9CCNKCNR2ABL1 | |
| SCHEMBL1948865 | 0.85 | CCNT1 (0.66) | CCNT1CDK9CCNK | |
| SCHEMBL1463028 | 0.83 | CCNT1 (0.67) | CCNT1CDK9 | |
| SCHEMBL1945863 | 0.83 | CCNT1 (0.52) | CCNT1CDK9CCNKCNR2 | |
| SCHEMBL10285490 | 0.82 | CCNT1 (0.53) | CCNT1CDK9CCNK | |
| SCHEMBL1439734 | 0.82 | CCNT1 (0.69) | CCNT1CDK9CCNK | |
| SCHEMBL10242723 | 0.82 | CDK9 (0.66) | CCNT1CDK9ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157433-A1 | Heteroaryl Compounds as Kinase Inhibitors | PFISTER KEITH B (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2011026917-A1 | HETEROARYL COMPOUNDS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157433-A1 | Heteroaryl Compounds as Kinase Inhibitors | CDK2, CDK1, CDK6 | CCNT1 80/4885CDK9 6/4885CCNK 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.