Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644168 | 0.90 | GRM5 (0.50) | GRM5 | |
| SCHEMBL531357 | 0.90 | GRM5 (0.50) | GRM5 | |
| SCHEMBL1643910 | 0.90 | GRM5 (0.50) | GRM5 | |
| SCHEMBL532340 | 0.90 | GRM5 (0.50) | GRM5 | |
| SCHEMBL10243305 | 0.89 | GRM5 (0.39) | GRM5 | |
| SCHEMBL13394575 | 0.89 | GRM5 (0.39) | GRM5 | |
| SCHEMBL13413309 | 0.89 | GRM5 (0.39) | GRM5 | |
| SCHEMBL13394573 | 0.89 | GRM5 (0.39) | GRM5 | |
| SCHEMBL1529100 | 0.89 | GRM5 (0.39) | GRM5 | |
| SCHEMBL12696882 | 0.83 | MGLL (0.37) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765793-B1 | ANACETRAPIB AND OTHER CETP INHIBITPRS | MERCK SHARP & DOHME (US) | 2012-09-26 | — | — | EP | disclosed |
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |