Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1024331

CC(C#N)CCC(=O)O.N

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.48
GABRD O14764 2/20 0.48
GABRA1 P14867 2/20 0.48
GABRB1 P18505 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRA3 P34903 2/20 0.48
GABRA2 P47869 2/20 0.48
GABRB2 P47870 2/20 0.48
GABRA4 P48169 2/20 0.48
GABRE P78334 2/20 0.48
GABRA6 Q16445 2/20 0.48
GABRG1 Q8N1C3 2/20 0.48
GABRG3 Q99928 2/20 0.48
GABRQ Q9UN88 2/20 0.48
CYP1A2 P05177 2/20 0.48
TSHR P16473 1/20 0.44
TET2 Q6N021 3/20 0.39
KDM4A O75164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28217929 1.00 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
Water SCHEMBL28240439 0.98 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL35490 0.98
Bromide SCHEMBL27544998 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
Hydrochloric Acid SCHEMBL7043007 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5050240 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27782375 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL30725511 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
Hydrochloric Acid SCHEMBL27835689 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28018620 0.95 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107938397-A A kind of cotton fabric strong water-fastness, rub resistance type ink and preparation method thereof 杭州海维特化工科技有限公司 2018-04-20 CN disclosed
CN-103261246-A Process for preparing a vinylidene chloride polymer latex SOLVAY 2013-08-21 CN disclosed
CN-101506251-B Process for preparing a chlorinated vinyl polymer latex SOLVAY 2012-05-16 CN disclosed
EP-1280892-B1 ISOLATION AND EXPRESSION OF A GENE FOR A NITRILASE FROM i ACIDOVORAX FACILIS 72W DU PONT (US) 2011-01-12 EP disclosed
CN-100558885-C Isolation and expression of nitrilase Gene of Acidovorax facilis 72W DU PONT (US) 2009-11-11 CN disclosed
CN-101506251-A Method for preparing a latex from a chlorinated vinylic polymer SOLVAY (BE) 2009-08-12 CN disclosed
CN-1308443-C Preparation of lactams from aliphatic alpha,omega dinitriles DU PONT (US) 2007-04-04 CN disclosed
EP-1466971-B1 Preparation of lactams from aliphatic alpha,omega dinitriles DU PONT (US) 2006-10-18 EP disclosed
US-7056709-B2 Isolation and expression of a gene for a nitrilase from Acidovorax faclilis 72W E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-06-06 US disclosed
CN-1253554-C Preparation of lactams from aliphatic alpha,omega dinitriles DU PONT (US) 2006-04-26 CN disclosed
US-6077955-A CONTACTING AN AQUEOUS PRODUCT MIXTURE CONTAINING A W-NITRILOCARBOXYLIC ACID AMMONIUM SALT WITH HYDROGEN AND A HYDROGENATION CATALYST, WHEREBY THE SALT IS CONVERTED DIRECTLY TO THE CORRESPONDING LACTAM WITHOUT ISOLATION OF INTERMEDIATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-20 US disclosed
US-6066490-A MICROORGANISMS THAT PRODUCES A HYDROLASE ENZYME THAT DEMONSTRATES PREFERENTIAL ACTIVITY E. I. DU PONT DE NEMOURS & COMPANY (US) 2000-05-23 US disclosed
US-5936114-A Preparation of lactams from aliphatic α, ω-dinitriles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-08-10 US disclosed
US-5922589-A ISOLATED COMAMONAS TESTOSTERONI 5-MGAM-4D WITH NITRILE HYDRATASE AND AMIDASE ACTIVITIES; FOR HIGH YIELD WITH HIGH REGIOSELECTIVITY AND BY PRODUCT INHIBITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-13 US disclosed
CN-1219167-A Preparation of Lactams from aliphatic alpha, omega-dinitriles DU PONT (US) 1999-06-09 CN disclosed
US-5908954-A CHEMICAL INTERMEDIATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-01 US disclosed
EP-0901468-A1 PREPARATION OF LACTAMS FROM ALIPHATIC $g(a),$g(v)-DINITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-17 EP disclosed
US-5858736-A CONTACTING DINITRILE IN AQUEOUS MIXTURE WITH ENZYME CATALYST HAVING ALIPHATIC NITRILASE ACTIVITY OR COMBINATION OF NITRILE HYDRATASE AND AMIDASE ACTIVITY, CONTACTING PRODUCT WITH HYDROGEN AND HYDROGENATION CATALYST TO PRODUCE LACTAM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed
US-5814508-A TREATING A WHOLE CELL CATALYST TO SELECT FOR A REGIOSELECTIVE NITRILASE ACTIVITY OR A NITRILE HYDRATASE ACTIVITY; CATALYTIC CONVERSION OF ALPHA-OMEGA DINITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-29 US disclosed
WO-1997044318-A1 PREPARATION OF LACTAMS FROM ALIPHATIC α,φ-DINITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-27 WO disclosed