SCHEMBL10243312

SCHEMBL10243312

COC(=O)CCN[C@@H](C)c1ccccc1OC

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 2/20 0.48
ACHE P22303 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
CA12 O43570 2/20 0.47
CA7 P43166 2/20 0.47
CA14 Q9ULX7 2/20 0.47
CA9 Q16790 1/20 0.47
LPAR1 Q92633 1/20 0.45
POLB P06746 1/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14063803 0.81 CYP1A2 (0.50) LMNAHTT
SCHEMBL10244611 0.81 HPGD (0.49) L3MBTL1CA1CA2ACHESMN1; SMN2
SCHEMBL2750779 0.80 CA12 (0.65) SMN1; SMN2LMNACA12CA7CA14
SCHEMBL23135630 0.80 CA12 (0.65) SMN1; SMN2LMNACA12CA7CA14
SCHEMBL15637303 0.78 SMN1; SMN2 (0.58) L3MBTL1CA1CA2ACHESMN1; SMN2
SCHEMBL335035 0.78 CA1 (0.53) L3MBTL1CA1CA2ACHESMN1; SMN2
SCHEMBL1989100 0.78 CA1 (0.49) L3MBTL1CA1CA2ACHESMN1; SMN2
SCHEMBL17024690 0.75 MC4R (0.43) SMN1; SMN2LMNACA12CA7CA14
SCHEMBL17024691 0.75 MC4R (0.43) SMN1; SMN2LMNACA12CA7CA14
SCHEMBL17029843 0.75 CA1 (0.53) L3MBTL1CA1CA2ACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 L3MBTL1 2853/4885CA1 3677/4885CA2 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.