SCHEMBL2750779

SCHEMBL2750779

COC(=O)CCNC(C)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CYP3A4 P08684 2/20 0.54
LMNA P02545 2/20 0.54
CASR P41180 2/20 0.54
CHRM2 P08172 1/20 0.54
HTR1A P08908 1/20 0.54
ADRA2A P08913 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
CHRM1 P11229 1/20 0.54
SMPD1 P17405 1/20 0.54
DRD1 P21728 1/20 0.54
TBXA2R P21731 1/20 0.54
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
ADRA1A P35348 1/20 0.54
OPRM1 P35372 1/20 0.54
DRD3 P35462 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23135630 1.00 CA12 (0.65) CA12CA7CA9CA14CYP3A4
SCHEMBL29016878 0.86 CYP3A4 (0.52) CA12CA7CA9CA14CYP3A4
SCHEMBL26018532 0.86 CYP3A4 (0.52) CA12CA7CA9CA14CYP3A4
SCHEMBL4331889 0.84 CA12 (0.49) CA12CA7CA9CA14CYP3A4
SCHEMBL27943340 0.84 CYP3A4 (0.59) CA12CA7CA9CA14CYP3A4
SCHEMBL25360452 0.84 CYP3A4 (0.59) CA12CA7CA9CA14CYP3A4
SCHEMBL2749557 0.84 CYP3A4 (0.59) CA12CA7CA9CA14CYP3A4
SCHEMBL2408159 0.83 APAF1 (0.57) CA12CA7CA9CA14CYP3A4
SCHEMBL6809830 0.83 APAF1 (0.57) CA12CA7CA9CA14CYP3A4
SCHEMBL2408156 0.83 APAF1 (0.57) CA12CA7CA9CA14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178712-B2 Process for the synthesis of Ibandronate sodium CIPLA LTD. (IN) 2012-05-15 US claimed
EP-2038291-B1 PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM CIPLA LTD (IN) 2010-07-14 EP claimed