SCHEMBL10243323

SCHEMBL10243323

CCc1ccc(-c2ccc(-c3ccc(C#N)cc3)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.86
TSHR P16473 1/20 0.61
HSD17B10 Q99714 1/20 0.61
LOXL2 Q9Y4K0 2/20 0.54
MMP3 P08254 1/20 0.52
KIF11 P52732 2/20 0.52
HRH3 Q9Y5N1 5/20 0.49
CYP19A1 P11511 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CYP11B2 P19099 2/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
MMP12 P39900 1/20 0.44
MMP13 P45452 1/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651866 1.00 CYP2A6 (0.86) CYP2A6TSHRHSD17B10LOXL2MMP3
Cyclohexane SCHEMBL27471978 0.94 CYP2A6 (0.76) CYP2A6TSHRHSD17B10LOXL2MMP3
SCHEMBL91062 0.93 CYP2A6 (1.00) CYP2A6TSHRHSD17B10LOXL2CYP19A1
SCHEMBL25188141 0.90 CYP2A6 (0.70) CYP2A6TSHRHSD17B10LOXL2MMP3
SCHEMBL14228591 0.89 CYP2A6 (0.68) CYP2A6TSHRHSD17B10HRH3
SCHEMBL7666462 0.86 CYP2A6 (0.86) CYP2A6TSHRHSD17B10LOXL2CYP19A1
SCHEMBL19743177 0.85 CYP2A6 (0.63) CYP2A6TSHRHSD17B10LOXL2KIF11
SCHEMBL10660521 0.84 CYP2A6 (0.61) CYP2A6TSHRHSD17B10LOXL2KIF11
SCHEMBL11457698 0.84 CYP2A6 (0.61) CYP2A6TSHRHSD17B10LOXL2KIF11
SCHEMBL14228600 0.83 CYP2A6 (0.60) CYP2A6TSHRHSD17B10HRH3CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
EP-4431989-A1 OPTICAL FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-09-18 EP disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
WO-2023090353-A1 OPTICAL FILM AND POLARIZING PLATE 東ソー株式会社 2023-05-25 WO disclosed
WO-2022210589-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE 東ソー株式会社 2022-10-06 WO disclosed
US-10196373-B2 Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2019-02-05 US disclosed
US-20150038708-A1 SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-02-05 US disclosed
US-8846707-B2 Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of stat protein UNIVERISTY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-09-30 US disclosed
WO-2012018868-A1 SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-02-09 WO disclosed
US-7923078-B2 Light-modulating liquid-crystal element ADEKA CORPORATION (JP) 2011-04-12 US disclosed
US-7923078-B2 Light-modulating liquid-crystal element ADEKA CORPORATION (JP) 2011-04-12 US disclosed
US-20090279043-A1 LIGHT-MODULATING LIQUID-CRYSTAL ELEMENT ADEKA CORPORATION (JP) 2009-11-12 US disclosed
US-20090279043-A1 LIGHT-MODULATING LIQUID-CRYSTAL ELEMENT ADEKA CORPORATION (JP) 2009-11-12 US disclosed
US-20090133746-A1 Solid-State Electrolyte Composition Containing Liquid Crystal Materials and Dye-Sensitized Solar Cells Using the Same JIN SUNG HO 2009-05-28 US disclosed
EP-1939268-A1 LIGHT-MODULATING LIQUID-CRYSTAL ELEMENT Adeka Corporation (JP) 2008-07-02 EP disclosed
EP-1116770-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY USING THE SAME DAINIPPON INK & CHEMICALS (JP) 2008-04-02 EP disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150038708-A1 SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN STAT3, STAT1, STAT4 CYP2A6 3172/4885TSHR 1268/4885HSD17B10 1696/4885
US-10196373-B2 Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein STAT3, STAT1, STAT4 CYP2A6 3172/4885TSHR 1268/4885HSD17B10 1696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.