Cyclohexane

Cyclohexane

SCHEMBL27471978

C1CCCCC1.CCc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.76

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.76
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
LOXL2 Q9Y4K0 2/20 0.48
HRH3 Q9Y5N1 7/20 0.48
KIF11 P52732 2/20 0.47
MMP3 P08254 1/20 0.47
KCNH2 Q12809 2/20 0.43
KCNJ1 P48048 1/20 0.43
CYP19A1 P11511 1/20 0.43
CYP11B2 P19099 1/20 0.42
KDM1A O60341 1/20 0.42
CTSC P53634 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651866 0.94 CYP2A6 (0.86) CYP2A6TSHRHSD17B10LOXL2HRH3
SCHEMBL10243323 0.94 CYP2A6 (0.86) CYP2A6TSHRHSD17B10LOXL2HRH3
SCHEMBL91062 0.87 CYP2A6 (1.00) CYP2A6TSHRHSD17B10LOXL2KCNH2
SCHEMBL25188141 0.85 CYP2A6 (0.70) CYP2A6TSHRHSD17B10LOXL2HRH3
SCHEMBL14228591 0.83 CYP2A6 (0.68) CYP2A6TSHRHSD17B10HRH3
SCHEMBL12141850 0.82 CYP2A6 (0.51) CYP2A6TSHRHSD17B10HRH3KIF11
SCHEMBL7666462 0.81 CYP2A6 (0.86) CYP2A6TSHRHSD17B10LOXL2KCNH2
SCHEMBL19743177 0.80 CYP2A6 (0.63) CYP2A6TSHRHSD17B10LOXL2HRH3
SCHEMBL11457698 0.79 CYP2A6 (0.61) CYP2A6TSHRHSD17B10LOXL2HRH3
SCHEMBL10660521 0.79 CYP2A6 (0.61) CYP2A6TSHRHSD17B10LOXL2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169138-A Novel liquid crystal compound bearing dienyl moiety and liquid crystal composition CHISSO CORP (JP) 1997-12-31 CN disclosed