⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026885 | 1.00 | — | — | |
| SCHEMBL19484930 | 0.97 | ALDH1A1 (0.40) | — | |
| SCHEMBL1024256 | 0.97 | — | — | |
| SCHEMBL28673966 | 0.97 | ALDH1A1 (0.40) | — | |
| SCHEMBL19485084 | 0.97 | ALDH1A1 (0.40) | — | |
| SCHEMBL23572609 | 0.97 | ALDH1A1 (0.40) | — | |
| SCHEMBL1023901 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL17701165 | 0.97 | ALDH1A1 (0.37) | — | |
| SCHEMBL1024258 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL30221107 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12172944-B2 | Process for the preparation of tapentadol and analogs thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-12-24 | — | — | US | claimed |
| US-20240002594-A1 | RING-OPENING POLYMERIZATIONS USING A FLOW REACTOR | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2024-01-04 | — | — | US | claimed |
| US-11807715-B2 | Ring-opening polymerizations using a flow reactor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2023-11-07 | — | — | US | claimed |
| EP-4247810-A1 | N-[(1,3-BENZOXAZOL-2-YL)-HETEROCYCLE]AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-09-27 | — | — | EP | claimed |
| CN-114907503-B | Photoinitiation system for aggregation state environment, photoinitiation polymeric material and application | 北京航空航天大学 | 2023-05-16 | — | — | CN | claimed |
| CN-114907503-A | Photoinitiation system for aggregation state environment, photoinitiation polymerization material and application | 北京航空航天大学 | 2022-08-16 | — | — | CN | claimed |
| US-20220177413-A1 | PROCESS FOR THE PREPARATION OF TAPENTADOL AND ANALOGS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-06-09 | — | — | US | claimed |
| WO-2022104510-A1 | TISSUE TRANSPARENTIZING REAGENT, PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳先进技术研究院 | 2022-05-27 | — | — | WO | claimed |
| WO-2022106680-A1 | N-[(1,3-BENZOXAZOL-2-YL)-HETEROCYCLE]AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-05-27 | — | — | WO | claimed |
| US-11286341-B2 | Ring-opening polymerizations using a flow reactor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2022-03-29 | — | — | US | claimed |
| US-20200407496-A1 | RING-OPENING POLYMERIZATIONS USING A FLOW REACTOR | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-12-31 | — | — | US | claimed |
| US-10815335-B2 | Ring-opening polymerizations using a flow reactor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-10-27 | — | — | US | claimed |
| CN-108569994-A | The synthetic method of 1,2- of one kind rings, penta dicarboximide | 滨海博大化工有限公司 | 2018-09-25 | — | — | CN | claimed |
| EP-1954674-B1 | NEW N-PHENETHYLCARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-03-16 | — | — | EP | claimed |
| US-20090239895-A1 | Novel 3-thia-10-aza-phenanthrene derivatives | NYCOMED GMBH (DE) | 2009-09-24 | — | — | US | claimed |
| US-20080103168-A1 | Novel 3-Thia-10-Aza-Phenanthrene Derivatives | ATLANA PHARMA AG (DE) | 2008-05-01 | — | — | US | claimed |
| EP-1791847-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | Altana Pharma AG (DE) | 2007-06-06 | — | — | EP | claimed |
| WO-2006027345-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | ALTANA PHARMA AG (DE) | 2006-03-16 | — | — | WO | claimed |
| EP-1216705-A2 | The use of growth factor modulation compounds substituted with three vicinal phosphorus containing radical in the manufacture of a medicament for tissue repair | PERSTORP AB (SE) | 2002-06-26 | — | — | EP | claimed |
| CN-1082449-C | Liquid jet recording head and process for production thereof | CANON KK (JP) | 2002-04-10 | — | — | CN | claimed |