Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220536 | 0.92 | GAA (0.56) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL8576726 | 0.87 | GAA (0.49) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL27972232 | 0.86 | TSHR (0.55) | GAAMGAMSIMGAM2POLB | |
| SCHEMBL14902246 | 0.85 | GAA (0.46) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL5571264 | 0.84 | KMT2A (0.52) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL12999490 | 0.84 | GAA (0.59) | GAACYP1A2L3MBTL1POLBMAPT | |
| SCHEMBL16744039 | 0.83 | GAA (0.45) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL15726347 | 0.82 | CASP2 (0.52) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL4432951 | 0.82 | GAA (0.48) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL5411539 | 0.82 | GAA (0.48) | GAAMGAMSIMGAM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085167-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-06-28 | — | — | WO | disclosed |