SCHEMBL1024478

SCHEMBL1024478

CC(CO)(C(N)=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.59
KMT2A Q03164 1/20 0.59
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
HTT P42858 1/20 0.44
KCNN4 O15554 7/20 0.43
TAAR1 Q96RJ0 1/20 0.42
CYP2D6 P10635 2/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
KCNH2 Q12809 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27815326 0.84 MAPT (0.59) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL15397577 0.84 MAPT (0.59) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL2030597 0.84 MAPT (0.59) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL6758034 0.83 CYP2C19 (0.50) MAPTKMT2ACYP2C19HIF1AKCNN4
SCHEMBL7385247 0.82 MAPT (0.57) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL12505244 0.82 KMT2A (0.52) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL2845811 0.81 MAPT (0.55) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL528412 0.81 KMT2A (0.55) MAPTKMT2ACYP2C19HIF1AHTT
SCHEMBL25304575 0.80 KMT2A (0.44) MAPTKMT2ACYP2C19HIF1AKCNN4
SCHEMBL17593429 0.79 MAPT (0.53) MAPTKMT2ACYP2C19HIF1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923398-B1 Process for producing a polypeptide CHISSO CORP (JP) 2011-01-05 EP disclosed
EP-1340767-B9 Polypeptide useful as biomaterial and process for producing the same CHISSO CORP (JP) 2009-08-19 EP disclosed
US-7544781-B2 Polypeptide and process for producing the same PHG CORPORATION (JP) 2009-06-09 US disclosed
EP-1340767-B1 Polypeptide useful as biomaterial and process for producing the same PHG CORP (JP) 2009-01-28 EP disclosed
EP-1923398-A1 Process for producing a polypeptide PHG Corporation (JP) 2008-05-21 EP disclosed
EP-1908828-A1 NOVEL POLYPEPTIDE AND METHOD FOR PRODUCING THE SAME PHG Corporation (JP) 2008-04-09 EP disclosed
US-20080009604-A1 Novel polypeptide and process for producing the same UNIQS CORPORATION (JP) 2008-01-10 US disclosed
US-20070207180-A1 Synthetic polypeptide-containing bioapplicable material and film-forming material PHG CORPORATION (JP) 2007-09-06 US disclosed
US-20070207955-A1 Novel polypeptide and process for producing the same, and collagenase inhibitor PHG CORPORATION (JP) 2007-09-06 US disclosed
US-7262275-B2 Polypeptide and process for producing the same PHG CORPORATION (JP) 2007-08-28 US disclosed
EP-0642666-B2 HEPATITIS C ASSAY ABBOTT LAB (US) 2004-08-11 EP disclosed
EP-1340767-A2 Polypeptide useful as biomaterial and process for producing the same CentMed Inc. (JP) 2003-09-03 EP disclosed
US-20030162941-A1 Novel polypeptide and process for producing the same UNIQS CORPORATION (JP) 2003-08-28 US disclosed
EP-0705245-A1 NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES MERRELL PHARMACEUTICALS INC. (US) 1996-04-10 EP disclosed
WO-1995000480-A1 NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES MERRELL PHARMACEUTICALS INC. (US) 1995-01-05 WO disclosed