SCHEMBL6758034

SCHEMBL6758034

CC(CO)(C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.50
HIF1A Q16665 1/20 0.50
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 4/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CYP2D6 P10635 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
KCNN4 O15554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1024478 0.83 MAPT (0.59) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL29074082 0.83 ESR1 (0.50) KMT2AALDH1A1TSHRESR1ESR2
SCHEMBL1492728 0.83 CYP2C19 (0.50) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL27759681 0.82 CES1 (0.50) CYP2C19HIF1AMAPTKMT2AHDAC3
SCHEMBL15109990 0.82 MEN1 (0.43) MAPTKMT2AKCNN4KIF11MAPK1
SCHEMBL27825524 0.82 OPRM1 (0.49) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL7097465 0.82 MIF (0.48) CYP2C19MAPTKMT2ACYP1A2CYP2D6
SCHEMBL20176120 0.82 HIF1A (0.46) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL23453194 0.81 TAAR1 (0.54) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL3719792 0.81 CYP2C19 (0.64) CYP2C19HIF1AMAPTKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11315064-A None JP disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
WO-2022242779-A1 BIOMARKER COMBINATION FOR ASSESSING RISK OF ADENOMA AND COLORECTAL CANCER, AND USE THEREOF 深圳市绘云生物科技有限公司 2022-11-24 WO disclosed
US-10144004-B2 Method for producing catalyst composition for hydrogenation and catalyst composition for hydrogenation ASAHI KASEI CHEMICALS CORPORATION (JP) 2018-12-04 US disclosed
US-10016749-B2 Catalyst composition for hydrogenation and method for hydrogenation using the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2018-07-10 US disclosed
EP-2898949-B1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD USING SAID HYDROGENATION CATALYST COMPOSITION ASAHI CHEMICAL IND (JP) 2018-04-04 EP disclosed
EP-2898950-B1 CATALYST COMPOSITION FOR HYDROGENATION AND HYDROGENATION METHOD USING CATALYST COMPOSITION FOR HYDROGENATION ASAHI CHEMICAL IND (JP) 2017-11-08 EP disclosed
EP-2913348-B1 METHOD OF PRODUCING HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION CATALYST COMPOSITION ASAHI CHEMICAL IND (JP) 2017-09-20 EP disclosed
US-9522393-B2 Catalyst composition for hydrogenation and method for hydrogenation using the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-12-20 US disclosed
US-20150298112-A1 METHOD FOR PRODUCING CATALYST COMPOSITION FOR HYDROGENATION AND CATALYST COMPOSITION FOR HYDROGENATION ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-10-22 US disclosed
CN-1827598-A Substituted benzyl ester and its preparation process and novel process for preparing substituted mopipe therefrom TIANJIN TAIPU PHARMACEUTICAL S (CN) 2006-09-06 CN disclosed
US-6720079-B2 THERMOSETTING POWDER COMPOSITION INCLUDING EPOXIDE CROSSLINKER AND POLYESTER HAVING TERMINAL TERTIARY CARBOXYL GROUPS FORMED BY REACTING PREPOLYESTER WITH COMPOUND HAVING TERTIARY CARBOXYL GROUP AND ANOTHER CARBOXYL GROUP OR HYDROXYL GROUP UCB, S.A. (BE) 2004-04-13 US disclosed
US-20030148130-A1 Surface appearance, good flexibility and good resistance to poor weather conditions. MOENS LUC (BE) 2003-08-07 US disclosed
US-6461742-B1 THERMOSETTING POWDER COMPOSITION, COMPRISING BETA-HYDROXYALKYLAMIDE CROSSLINKING AGENT AND POLYESTER HAVING TERMINAL TERTIARY CARBOXYL GROUPS, HAVING SPECIFIED ACID NUMBER UCB, S.A. (BE) 2002-10-08 US disclosed
CN-1293686-A Polyester containing tertiary carboxyl groups, preparation method and thermosetting powder compositions containing same UCB SA (BE) 2001-05-02 CN disclosed
EP-1091938-A2 ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF Aventis Pharmaceuticals Inc. (US) 2001-04-18 EP disclosed
WO-2000001671-A2 ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF AVENTIS PHARMACEUTICALS INC. (US) 2000-01-13 WO disclosed
JP-H11315064-A PRODUCTION OF OPTICALLY ACTIVE PHENYLPROPIONIC ACID DERIVATIVE AJINOMOTO CO INC 1999-11-16 JP disclosed
EP-0705245-A1 NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES MERRELL PHARMACEUTICALS INC. (US) 1996-04-10 EP disclosed
WO-1995000480-A1 NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES MERRELL PHARMACEUTICALS INC. (US) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10016749-B2 Catalyst composition for hydrogenation and method for hydrogenation using the same H1-0, H1-2, HVCN1 CYP2C19 2138/4885HIF1A 501/4885MAPT 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.