Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 10/20 | 0.81 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391540 | 0.92 | IDH2 (0.81) | IDH2APPLMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL3103521 | 0.91 | IDH2 (0.79) | IDH2APPLMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL1391637 | 0.91 | IDH2 (0.79) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1391965 | 0.91 | IDH2 (0.64) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1392078 | 0.89 | IDH2 (0.62) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1392755 | 0.88 | IDH2 (0.62) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1391626 | 0.88 | IDH2 (0.62) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1391058 | 0.88 | IDH2 (0.62) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1392914 | 0.88 | IDH2 (0.61) | IDH2APPLMNAMAPTMAPK1 | |
| SCHEMBL1391993 | 0.88 | IDH2 (0.61) | IDH2APPLMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | HAVCR2, ZC3HAV1, MAVS | IDH2 1936/4885APP 4146/4885LMNA 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.