Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 8/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204362 | 0.91 | EPHX1 (0.37) | EPHX1TSHRTHRBGGPS1PPARA | |
| SCHEMBL9213836 | 0.83 | EPHX1 (0.42) | EPHX1TSHRTHRBGGPS1PPARA | |
| SCHEMBL9206460 | 0.83 | EPHX1 (0.42) | EPHX1TSHRTHRBGGPS1PPARA | |
| SCHEMBL9206621 | 0.83 | EPHX1 (0.37) | EPHX1TSHRTHRBGGPS1ALDH1A1 | |
| SCHEMBL115537 | 0.82 | LMNA (0.41) | TSHRGGPS1ALDH1A1FDPSCES2 | |
| SCHEMBL515592 | 0.82 | LMNA (0.41) | TSHRGGPS1ALDH1A1FDPSCES2 | |
| Hydrochloric Acid SCHEMBL11863080 | 0.81 | EPHX1 (0.41) | EPHX1TSHRTHRBALDH1A1ADH1B | |
| SCHEMBL27670693 | 0.80 | TSHR (0.36) | EPHX1TSHRTHRBGGPS1ALDH1A1 | |
| SCHEMBL117144 | 0.80 | LMNA (0.44) | EPHX1TSHRGGPS1ALDH1A1FDPS | |
| SCHEMBL16975497 | 0.78 | TSHR (0.36) | TSHRALDH1A1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810972-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2012-01-25 | — | — | EP | disclosed |