Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 12/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481061 | 0.93 | CYP2C9 (0.47) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL10245928 | 0.90 | CYSLTR1 (0.44) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481077 | 0.89 | SMN1; SMN2 (0.43) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481162 | 0.88 | GRM2 (0.49) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481386 | 0.87 | GRM2 (0.47) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755718 | 0.86 | GRM2 (0.41) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481561 | 0.85 | GRM2 (0.60) | CYSLTR1GRM2CYSLTR2MRGPRX4 | |
| SCHEMBL27686256 | 0.85 | GRM2 (0.49) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481247 | 0.85 | MAPT (0.47) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481129 | 0.83 | PTGER1 (0.47) | CYP2C9MAPTCYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817301-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2012-02-01 | — | — | EP | disclosed |