Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481129 | 0.93 | PTGER1 (0.47) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL10246006 | 0.90 | CYP2C9 (0.46) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL481052 | 0.90 | SMPD1 (0.45) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL1755744 | 0.87 | SMPD1 (0.41) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL481341 | 0.87 | CYSLTR1 (0.59) | CYSLTR1GRM2CYSLTR2 | |
| SCHEMBL27686260 | 0.86 | PTGER1 (0.47) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL481061 | 0.83 | CYP2C9 (0.47) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL10245317 | 0.81 | MAPT (0.51) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL481077 | 0.80 | SMN1; SMN2 (0.43) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 | |
| SCHEMBL481369 | 0.80 | PTGER1 (0.43) | CYSLTR1GRM2CYP2C9MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817301-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2012-02-01 | — | — | EP | disclosed |